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Who acts Karen Wheeler? Which actress takes on the role of Karen Wheeler in the show? Who is the performer behind Karen Wheeler? Mrs. Wheeler is depicted by who? What actress plays the character of Karen the mother on the series? Whom is the talent showcasing Karen the mother's character to life? Which actress takes on the role of Karen Wheeler in the series? Whoever takes on the part of Karen Mrs. Wheeler? Who is the talented individual enacting Karen Wheeler on the series? What actress incarnates the character of Karen Mrs. Wheeler to the screen?